Heating, ventilating and air-conditioning (HVAC) systems in buildings must be integrated with an efficient control scheme to maintain comfort under any load conditions. Efficient HVAC control is often the most cost-effective option to improve the energy efficiency of a building. However, HVAC processes are non-linear, and characteristics change on a seasonal basis so the effect of changing the control strategy is usually difficult to predict. The present study aims to reduce energy consumption by defining new HVAC control strategies and tuning control loops in a shopping centre. First, an energy audit was performed to investigate the potential for energy savings and to redefine the control scenarios, while a methodology for the shopping centre was developed. Performance indices were then calculated and compared with the yardsticks. Next, normalised performance indices were computed to reach out a better understanding of the building’s efficiency. Finally, new strategies were implemented with the help of the existing building management system (BMS) and about 22% of energy saving was achieved.